2022年第12期摘要:通过在苹果醋中添加山楂汁、枸杞汁、木糖醇、柠檬酸钠等原料,开发一种复合型功能饮料,并对其降血脂功效进行评价。以感官评分为指标,采用单因素试验结合响应面法优化该饮料配方,将50只KM小鼠随机分为5组,连续喂养4周,边造模边给药,检测小鼠血清中血脂含量的变化。结果表明,4周后,小鼠血清中血脂含量有显著变化。山楂枸杞苹果醋复合饮料对高血脂小鼠模型有显著的改善作用,揭示了其对血脂异常及由血脂异常造成的心脑血管疾病等有一定的保健作用。关键词:山楂枸杞苹果醋复合饮料;响应面试验;降血脂中图分类号:F316.5文献标志码:Adoi:10.16693/j.cnki.1671-9646(X).2022.12.032DevelopmentofHawthornandWolfberryAppleVinegarBeverageanditsLipid-loweringEfficacyEvaluationWANGPei,CHENLing,GUOZhanbin,*XUNingxia,WANGHanping(Xi'anIntermationalUniversityMcdicalCollege,Xi'an,Shaanxi710077,China)Abstract:Todevelopacompoundfunctionalbeveragebyaddinghawthornjuice,wolfberryjuice,xylitol,sodiumcitrateandotherrawmaterialsinapplevinegar,andevaluateitslipid-loweringeffect.Withsensoryscoreastheindex,theformulaofthebeveragewasoptimizedbysinglefactortestcombinedwithresponsesurfacemethodology.FiftyKMmicewererandomlydividedintofivegroups.Theywerecontinuouslyfedforfourweeks,andthechangesinserumlipidcontentweredetectedwhilemod-elingandadministration.After4weeks,theserumlipidcontentofmicehadsignificantchanges.Hawthorn,wolfberryandapplevinegarcompoundbeveragehadasignificantimprovementonhyperlipidemiamousemodel,revealingthatitcouldhaveacertainhealtheffectondyslipidemiaandcardiovascularandcerebrovasculardiseasescausedbydyslipidemia.Keywords:hawthornwolfberryapplevinegarcompoundbeverage;responsesurfaceexperiment;hypolipidemic.山楂枸杞苹果醋复合饮料研制及其降血脂功效评价王培,陈伶,郭占斌,*许宁侠,王汉屏(西安外事学院医学院,陕西西安710077)收稿日期:2022-01-14基金项目:陕西省教育厅科学研究计划项目(21JK0866);陕西省重点研发计划项目(2019NY-156)。作者简介:王培(1990—),女,硕士,助教,研究方向为农产品加工。*通讯作者:许宁侠(1973—),女,博士,副教授,研究方向为天然产物活性成分提取...