98·中国CT和MRI杂志2023年02月第21卷第02期总第160期【第一作者】田甜，女，主治医师，主要研究方向：放射影像诊断。E-mail：tiant202203@126.com【通讯作者】云昊，男，主治医师，主要研究方向：放射影像诊断。E-mail：981523387@qq.com论著RelationshipbetweenSignalIntensityHistogramofGlobalDiffusionCoefficientandPathologicalStageinBreastCancerandItsPredictiveValueforRecurrenceTIANTian,YUNHao*,WANGShan,LUOFa-fu.DepartmentofRadiology,WenchangPeople'sHospital,Wenchang571399,HainanProvince,ChinaABSTRACTObjectiveToexploretherelationshipbetweentheglobalapparentdiffusioncoefficient(ADC)signalintensityhistogramandpathologicalstageofbreastcanceranditspredictivevalueforrecurrence.MethodsTheclinical,pathologicalandimagingdataof90patientswithinvasiveductalcarcinomatreatedinourhospitalfromJune2016toJuly2020wereretrospectivelycollected,allpatientsunderwentMRIexamination.ApplySiemensworkstationtorebuildADCimage,Extract3Dregionofinterest(ROI)ADCminimumvalue(ADCmin),ADCmedian(ADCmedian),ADCmean(ADCmean),ADCmode(ADCmode),ADCstandarddeviation(ADCstd),ADCmaximumvalue(ADCmax),,10thpercentile(ADC10%),25thpercentile(ADC25%),50thpercentile(ADC50%),75thpercentile(ADC75%),90thpercentile(ADC90%),skewnesscoefficientandkurtosiscoefficientandotherparameters.Thepatientsweredividedintogroupsaccordingtotumorpathologicaltypeandpostoperativerecurrence,thedifferencesbetweenthegroupswerecompared,andthediagnosticandpredictiveefficacyofADChistogramparameterswasevaluatedbydrawingreceiveroperatingcharacteristiccurve(ROC).ResultsADC25%,ADC50%andADC95%instageT1-T2groupweresignificantlylowerthanthoseinstageT3-T4group,andthekurtosiscoefficientwassignificantlyhigherthanthatinstageT3-T4group,withstatisticalsignificance(P<0.05).InADChistogram,thediagnosticefficacyofADC95%indistinguishingdifferentpathologicalstagesofbreastcancerwasthebest.Whenthebestdiagnosticthresholdwas1.363×10-3mm2/s,theareaunderthecurvewas0.869,andthecorrespondingYoudenindex,sensitivityandspecificitywere0.741,88.50%and85.60%,respectively.Comparedwiththen...
