临床医学研究与实践2023年3月第8卷第7期Analysisoftheuseofnewanti-tumordrugsbasedonParetoanalysisanddefineddailydosemethodCHENQun,YANYuanyuan,YANGXiaopeng,XIQing*(PharmaceuticalDepartment,AviationGeneralHospital,Beijing100012,China)ABSTRACT:ObjectiveParetoanalysisanddefineddailydose(DDD)methodwereusedtoanalyzetheuseofnewanti-tumordrugsinatertiaryhospitalinBeijingfrom2019to2021,soastoprovidedatasupportandreferenceforclinicalrationaluse.MethodsThedataofvarieties,specifications,dosageforms,quantityandamountofnewanti-tumordrugsfromJanuary2019toDecember2021werecollected,andtheamountandconstituentratio,defineddailydosesystem(DDDs),defineddailycost(DDC)andrankingratio(B/A)ofalltumordrugswerecalculatedusingExcel.ResultsDuringthethreeyears,thenumberofnewtargetedanti-tumordrugsincreasedfrom16in2019to20in2021,andtheamountalsoincreasedfrom3.4436millionyuanin2019to6.1132millionyuanin2021,anincreaseof77.52%year-on-year;thevarietyofclassAdrugswasstableatabout4,andmacromolecularmonoclonalantibodyweremorethansmallmoleculetargeteddrugs;theDDDsofeachdrugincreasedsignificantly,amongwhichtrastuzumab,patuzumabandgefitinibrankedthetop.In2021,exceptforbevacizumas,theB/AofclassAdrugswereequalto1.ConclusionTheuseofnewtargetedanti-tumordrugsinatertiaryhospitalinBeijingwasbasicallyreasonable.TheB/AofclassAdrugswasmostlyequaltoorcloseto1,andtheamountofusewasconsistentwithDDDs,withgoodsynchronization.KEYWORDS:newanti-tumordrug;Paretoanalysis;defineddailydosemethod;defineddailydosesystem;defineddailycost基于帕雷托分析法和限定日剂量法分析新型抗肿瘤药物的使用陈群，闫园园，杨晓鹏，席庆*（航空总医院药学部，北京，100012）摘要：目的利用帕雷托分析法和限定日剂量（DDD）法分析北京某三级医院2019—2021年新型抗肿瘤药物使用情况，为临床合理使用提供数据支持和参考。方法收集2019年1月至2021年12月新型抗肿瘤药物的品种、品规、剂型、数量、金额等数据，使用Excel计算出所有肿瘤药品的金额及构成比、用药频度（DDDs）、限定日费用（DDC）及排序比（B/A）。结果3年间，新型靶向抗肿瘤药由2019年的16种增加到2021年的20种，金额也由2019年...
