山西医药杂志2023年1月第52卷第1期ShanxiMedJ,January2023,Vol.52.No.1阿司匹林联合依诺肝素治疗复发性流产妊娠结局效果分析刘婵华邓红云【摘要】目的观察阿司匹林联合依诺肝素对复发性流产妊娠结局的影响。方法选取我院2019年3月到2022年1月196例复发性流产妊娠患者为本次研究对象,根据用药不同将患者分为2组,对照组行阿司匹林治疗,试验组采用阿司匹林联合依诺肝素治疗,2组患者均应用黄体酮治疗,比较2组患者治疗效果。结果试验组患者治疗后子宫动脉血流参数、相关凝血指标以及妊娠成功率均优于对照组,此外,试验组围生儿不良结局发生率低于对照组,差异有统计学意义(P<0.05)。试验组患者不良反应发生率略高于对照组,差异无统计学意义(P>0.05)。结论对于复发性流产患者阿司匹林联合依诺肝素的应用可显著改善妊娠结局。【关键词】阿司匹林;依诺肝素;流产,习惯性;妊娠结局DOI:10.3969/j.issn.0253-9926.2023.01.007作者单位:362261福建省晋江市安海医院妇产科TheeffectofaspirincombinedwithenoxaparinonthepregnancyoutcomeofrecurrentabortionLiuChan-hua,DengHongyun.DepartmentofObstetricsandGynecology,JinjiangAnhaiHospitalofFujianProvince,Fujian362261,China【Abstract】ObjectiveToobservetheeffectofaspirincombinedwithenoxaparinonthepregnancyoutcomeofrecurrentabortion.MethodsOnehundredandninty-sixrecurrentabortionpregnancypatientsinourhospitalfromMarch2019toJanuary2022wereselectedforthestudyobject,accordingtowhethertheapplicationofaspirincom-binedwithenoxaparintreatment,thepatientsweredividedintocontrolgroupandexperimentalgroup,bothgroupsofpatientsweretreatedwithprogesterone,thetreatmenteffectofthetwogroupswascompared.ResultsTheuterinearteryflowparameters,relatedcoagulationindexandpregnancysuccessrateintheexperimentalgroupwerebetterthanthoseofthecontrolgroup,andtheincidenceofperinataladverseoutcomesintheexperimentalgroupwaslowerthanthoseofthecontrolgroup,andthedataweresignificantlydifferent(P<0.05).Theincidenceofadversereactionsintheexperimentalgroupwasslightlyhigherthanthatinthecontrolgroup,butthedifferenceswerenotsignificant(P>0.05).ConclusionTheapplicationofaspirinandenoxaparincansignificantlyimprovepregnancyoutcomes.【...