2023年4月第30卷第4期氨甲环酸注射液联合垂体后叶素预防前置胎盘产妇产后出血的效果及对凝血功能的影响白亚娟，范慧敏，苗红艳（三门峡市中心医院产科，河南三门峡472000）【摘要】目的探讨氨甲环酸注射液联合垂体后叶素预防前置胎盘产妇产后出血的效果及对凝血功能的影响。方法58例行剖宫产的前置胎盘产妇随机分为两组各29例。在胎儿娩出后，对照组注射垂体后叶素，观察组在对照组基础上给予氨甲环酸注射液。比较两组的产后出血量和凝血功能。结果观察组产后2h、24h的出血量均低于对照组（P<0.05）。产后24h，两组的APTT、PT均较分娩前缩短，FIB水平均较分娩前升高（P<0.05）；且观察组的APTT、PT均短于对照组，FIB水平高于对照组（P<0.05）。结论氨甲环酸注射液联合垂体后叶素预防前置胎盘产妇产后出血效果较好，能有效改善产妇的凝血功能。【关键词】前置胎盘；产后出血；氨甲环酸注射液；垂体后叶素；凝血功能中图分类号：R714.46+1文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.04.0499EffectofTranexamicAcidInjectionCombinedwithPituitrinonPreventionofPostpartumHemorrhageinPregnantWomenwithPlacentaPreviaandItsImpactonCoagulationFunction//BAIYajuan,FANHuimin,MIAOHongyan(DepartmentofObstetrics,SanmenxiaCentralHospital,Sanmenxia472000,China)[Abstract]ObjectiveToexploretheeffectoftranexamicacidinjectioncombinedwithpituitrinonpreventionofpostpartumhemorrhageinpregnantwomenwithplacentapreviaanditsimpactoncoagulationfunction.Methods58pregnantwomenwithplacentapreviawhounderwentcesareansectionwererandomlydividedintotwogroups,with29casesineachgroup.Afterthefetuswasdelivered,thecontrolgroupwasinjectedwithpituitrin,andtheobservationgroupwasgiventranexamicacidinjectiononthebasisofthecontrolgroup.Thepostpartumhemorrhageamountandcoagulationfunctionwerecomparedbetweenthetwogroups.ResultsThehemorrhageamountat2hand24hafterdeliveryintheobservationgroupwerelowerthanthoseinthecontrolgroup(P<0.05).At24hafterdelivery,theAPTTandPTofthetwogroupswereshorterthanthosebeforedelivery,andtheFIBlevelswerehigherthanthosebeforedelivery(P<0.05);TheAPTTandPTintheobservationgroupwereshorterthanthoseinthecontrolgroup,andtheFIBlevelwashigherthanthatinthecontrolgroup(P<...
