2023年4月第30卷第4期B族链球菌核酸检测在产前筛查中的应用黎金凤，赵俏猷，梁慧玲（茂名市电白区妇幼保健院检验科，广东茂名525400）【摘要】目的探讨B族链球菌核酸检测在产前筛查中的临床应用价值。方法选取2021年1月至2021年11月在我院产检及分娩的3996例产妇，在孕35～37周时采集其肛周与阴道分泌物进行PCR检查，统计B族链球菌的阳性检出率，比较B族链球菌阳性组、B族链球菌阴性组的分娩状况及母婴并发症发生情况。结果3996例产妇中，360例产妇检出B族链球菌，阳性检出率为9．01％。B族链球菌阳性组的顺产率低于B族链球菌阴性组，剖宫产率高于B族链球菌阴性组（P＜0．05）。B族链球菌阳性组的产妇并发症总发生率、新生儿并发症总发生率均高于B族链球菌阴性组（P＜0．05）。结论产前筛查中应用B族链球菌核酸检测利于指导临床科学干预，降低母婴并发症发生风险，降低剖宫产率，改善分娩结局。【关键词】B族链球菌；核酸检测；产前筛查；并发症；分娩结局中图分类号：R715.5文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.04.0583ApplicationofGroupBStreptococcusNucleicAcidDetectioninPrenatalScreeningLIJinfeng,ZHAOQiaoyou,LIANGHuiling(ClinicalLaboratory,DianbaiDistrictMaternalandChildHealthHospital,Maoming525400,China)[Abstract]ObjectiveToexploretheclinicalapplicationvalueofgroupBstreptococcusnucleicaciddetectioninprenatalscreening.MethodsFromJanuary2021toNovember2021,3996pregnantwomenwhounderwentprenatalexaminationanddeliveryinourhospitalwereselected.TheperianalandvaginalsecretionswerecollectedforPCRexaminationat35~37weeksofgestation.ThepositivedetectionrateofgroupBstreptococcuswascounted,andthedeliverystatusandthematernalandinfantcomplicationsofgroupBstreptococcuspositivegroupandgroupBstreptococcusnegativegroupwerecompared.ResultsAmong3996pregnantwomen,groupBstreptococcuswasdetectedin360pregnantwomen,withthepositivedetectionrateof9.01%.ThenaturalbirthrateofgroupBstreptococcuspositivegroupwaslowerthanthatofgroupBstreptococcusnegativegroup,andthecesareansectionratewashigherthanthatofgroupBstreptococcusnegativegroup(P<0.05).ThetotalincidenceofmaternalcomplicationsandthetotalincidenceofneonatalcomplicationsinthegroupBstreptococcuspositivegro...
