110·中国CT和MRI杂志2023年02月第21卷第02期总第160期【第一作者】熊健，男，副主任医师，主要研究方向：食管癌。E-mail：dengping711@163.com【通讯作者】熊健论著StudyontheRelationshipbetweenDCE-MRIQuantitativeParametersandPathologicalGradingofEsophagealCarcinoma*XIONGJian1,*,ZHENGLi-ming2,YUHan-cheng3,LUOShi4.1.DepartmentofRadiology,BeijingNanjiaoCancerHospital,DaxingDistrict,Beijing100162,China2.DepartmentofRadiology,BeijingNanjiaoCancerHospitalBeijing100076,China3.DepartmentofRadiology,JianshiHospitalofTraditionalChineseMedicine,EnshiPrefecture,Enshi445300,HubeiProvince,China4.DepartmentofRadiotherapy,PekingUniversityFirstHospitalBeijing100034,ChinaABSTRACTObjectiveToinvestigatetherelationshipbetweenquantitativeparametersofdynamiccontrast-enhancedmagneticresonanceimaging(DCE-MRI)anddifferentpathologicalgradesofesophagealcancer.MethodsAtotalof95patientswithesophagealcancertreatedbyradicalresectioninourhospitalfromDecember2017toDecember2019wereretrospectivelyselected,including19casesofG1grade,44casesofG2grade,and32casesofG3grade.Dce-mriexaminationwasperformedwithin1weekbeforeoperation.QuantitativeparametersofDCE-MRI[volumetransferconstant(Ktrans),rateconstant(Kep),maximum(Max),mean(mean),median75%(75%)ofextravascularextracellularspacevolumeratio(Ve)]weremeasured.ToanalyzetherelationshipbetweendifferentpathologicalgradesofesophagealcancerandquantitativeparametersofDCE-MRI.ResultsThereweresignificantdifferencesinKtrans,KepandVevaluesbetweendifferentpathologicalgradesofesophagealcancerandDCE-MRIquantitativeparameters(P<0.05).SpearmancorrelationanalysisshowedthatKtrans,KepandVevalueswerepositivelycorrelatedwithdifferentpathologicalgradesofesophagealcancer(P<0.05).ConclusionsTherearesignificantdifferencesinDCE-MRIquantitativeparametersinpatientswithdifferentpathologicalgradesofesophagealcancer,andthereisacertainrelationshipbetweenthem.Ktrans,KepandVevaluescanprovideacertainreferencevalueforbloodperfusionofesophagealcancerwithdifferentpathologicalgrades.Keywords:EsophagealNeo...
