《癌症进展》2022年12月第20卷第24期ONCOLOGYPROGRESS,Dec2022Vol.20,No.24*论著*CTCT引导下引导下125125I粒子植入治疗局部复发性宫颈癌的临床疗效粒子植入治疗局部复发性宫颈癌的临床疗效△张宋玲#，陈爱林，黄晶赣州市肿瘤医院影像科，江西赣州3410000摘要摘要：目的目的探讨CT引导下125I粒子植入治疗局部复发性宫颈癌的临床疗效。方法方法采用随机数字表法将70例局部复发性宫颈癌患者分为观察组和对照组，对照组患者采用以铂类为主的化疗方案，观察组患者在对照组的基础上予以CT引导下125I粒子植入治疗。比较两组患者的临床疗效、生存情况及不良反应发生情况。结果结果观察组患者的临床疗效优于对照组，差异有统计学意义（P﹤0.05）。观察组患者的生存情况优于对照组，差异有统计学意义（P﹤0.05）。两组患者各不良反应发生率比较，差异均无统计学意义（P﹥0.05）。结论结论CT引导下125I粒子植入治疗复发性宫颈癌的疗效确切，能够延长生存期，且安全性较高。关键词关键词：宫颈癌；125I粒子；临床疗效；生存情况中图分类号中图分类号：R737737.3333文献标志码文献标志码：AdoiAdoi：10.11877/j.issn.1672-1535.2022.20.24.07ClinicalefficacyofCT-guidedClinicalefficacyofCT-guided125125IparticleimplantationinlocallyrecurrentIparticleimplantationinlocallyrecurrentcervicalcancercervicalcancer△ZHANGSongling#,CHENAilin,HUANGJingDepartmentofImaging,GanzhouCancerHospital,Ganzhou341000,Jiangxi,ChinaAbstract:ObjectiveAbstract:ObjectiveToexploretheclinicalefficacyofCT-guided125Iparticleimplantationinlocallyrecurrentcervi-calcancer.MethodMethodAtotalof70patientswithlocallyrecurrentcervicalcancerwererandomlydividedintoobservationgroupandcontrolgroup,35casesineachgroup.Thecontrolgroupreceivedplatinumbasedchemotherapy,andobserva-tiongroupreceivedCT-guided125Iparticleimplantationonbasisofcontrolgroup.Theclinicalefficacy,survivalandinci-denceofadversereactionswerecomparedbetweenthetwogroups.ResultResultTheclinicalefficacyofobservationgroupwasbetterthanthatofcontrolgroup(P<0.05).Thesurvivalofpatientsinobservationgroupwasbetterthanthatofpa-tientsincontrolgroup(P<0.05).Therewerenosignificantdifferencesfortheincidenceofadversereactionsbetweenthetwogroups(P>0.05).Conc...
