2021年某3所院校新入学学员尿毒品检测假阳性结果分析张淑艳1,王红雷1,高蕾1,袁小美1,刘杰2(1.解放军总医院京东医疗区医技保障科,北京100191;2.解放军总医院第七医学中心检验科,北京100700)DOI:10.11748/bjmy.issn.1006-1703.2022.11.012收稿日期:2022-08-17;修回日期:2022-09-09基金项目:我军生物安全病原监测与应用处置关键技术研究(编号:AWS16J020)摘要:目的对某3所军队院校新入学学员尿毒品检测中出现的假阳性结果进行分析并探讨造成假阳性的干扰因素,给出规避假阳性结果的合理化建议。方法采用胶体金法对军队院校3665例新入学学员进行尿液中吗啡、甲基安非他明和氯胺酮毒品检测,对出现假阳性的8例阳性反应者结合身体健康状况,调查用药史和特殊饮食情况,嘱咐停药3、5d后采用同方法、同试剂复查尿毒品两次。结果3665例样本中,检出阳性反应者8例(6例吗啡阳性,2例甲基安非他明阳性),阳性率为0.22%;8例初筛反应阳性者停用任何药物3、5d后复测尿毒品,两次检测结果全部为阴性。结论胶体金法检测尿毒品造成假阳性的干扰因素主要为服用药物导致,包括感冒药、止咳药、胃痛药和鼻炎药。院校应加强学员体检前的宣传教育,应在体检前3d停止用药,以免因用药出现尿毒品检测假阳性对学员造成心理负担。关键词:尿液毒品检测;胶体金法;假阳性;原因分析中图分类号:R446.12文献标识码:AAnAnalysisofFalsePositiveResultsofUrineDrugTestofNewStudentsfromThreeCollegesin2021ZHANGShuyan1,WANGHonglei1,GAOLei1,YUANXiaomei1,LIUJie2(1.DepartmentofMedicalTechnologyandSupport,JingdongMedicalDistrict,PLAGeneralHospital,Beijing100191,China;2.DepartmentofClinicalLaboratory,SeventhMedicalCenter,PLAGeneralHospital,Beijing100700,China)Abstract:ObjectiveToanalyzethefalsepositiveresultsinurinedrugtestingofnewrecruitsinthreemilitarycollegesandtoexploretheinterferencefactorscausingfalsepositiveresults,andtofurtherprovidereasonablesuggestionstoavoidfuturefalsepositiveresults.MethodsUsingcolloidalgoldmethodfor3665newentrancestudentsinmilitaryacademiesandschoolsintheurinemorphine,methylamphetamineandketaminedrugtesting,weevaluatedfalsepositiveresultsof8casesofpositivereactionincombinationwiththeirphysicalhealth,medicationhistoryandspecialdiets,aswellaschargewithdrawalforthreedays,fivedays,thencheckedwiththe...
