15(11):e0242809.NielsenMS,AxelsenLN,SorgenPL,etal.Gapjunctions[J].ComprPhysiol,2012,2(3):1981-2035.[17]SchajnovitzA,ItkinT,D'UvaG,etal.CXCL12secretionbybonemarrowstromalcellsisdependentoncellcontactandmediatedbyconnexin-43andconnexin-45gapjunctions[J].NatImmunol,2011,12(5):391-398.[18]KouziF,ZibaraK,BourgeaisJ,etal.Correction:Disruptionofgapjunctionsattenuatesacutemyeloidleukemiachemoresistancein-ducedbybonemarrowmesenchymalstromalcells[J].Oncogene,2020,39(10):2227.[19]CaivanoA,LaRoccaF,LaurenzanaI,etal.Extracellularvesiclesinhematologicalmalignancies:frombiologytotherapy[J].IntJMolSci,2017,18(6):E1183.[20]TrinoS,LamorteD,CaivanoA,etal.Clinicalrelevanceofextracel-lularvesiclesinhematologicalneoplasms:fromliquidbiopsytocellbiopsy[J].Leukemia,2021,35(3):661-678.[21]NehrbasJ,ButlerJT,ChenDW,etal.ExtracellularvesiclesandchemotherapyresistanceintheAMLmicroenvironment[J].FrontOncol,2020,10:90.[22]LyuTX,WangYN,LiD,etal.ExosomesfromBM-MSCspromoteacutemyeloidleukemiacellproliferation,invasionandchemores-istanceviaupregulationofS100A4[J].ExpHematolOncol,2021,10(1):24.[23]ViolaS,TraerE,HuanJY,etal.Alterationsinacutemyeloidleuk-aemiabonemarrowstromalcellexosomecontentcoincidewithgainsintyrosinekinaseinhibitorresistance[J].BrJHaematol,2016,172(6):983-986.[24]XuYC,LinYS,ZhangL,etal.microRNAsofbonemarrowmesen-chymalstemcell-derivedexosomesregulateacutemyeloidleuk-emiacellproliferationandapoptosis[J].ChinMedJ(Engl),2020,133(23):2829-2839.[25]ChengH,DingJ,TangGS,etal.HumanmesenchymalstemcellsderivedexosomesinhibitthegrowthofacutemyeloidleukemiacellsviaregulatingmiR-23b-5p/TRIM14pathway[J].MolMed,2021,27(1):128.[26]ZhangF,LuY,WangM,etal.ExosomesderivedfromhumanbonemarrowmesenchymalstemcellstransfermiR-222-3ptosuppressacutemyeloidleukemiacellproliferationbytargetingIRF2/INPP4B[J].MolCellProbes,2020,51:101513.[27]ZhangL,KhadkaB,WuJY,etal.Bonemarrowmesenchymalstemcells-derivedexosomalmiR-425-5pinhibitsacutemyeloidleuk-emiacellproliferation,apoptosis,invasionandmigrationbytar-getingWT...
