ISO/ASTM51939:2017(E)StandardPracticeforBloodIrradiationDosimetry1ThisstandardisissuedunderthefixeddesignationISO/ASTM51939;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.1.Scope1.1Thispracticeoutlinestheirradiatorinstallationqualifi-cationprogramandthedosimetricprocedurestobefollowedduringoperationalqualificationandperformancequalificationoftheirradiator.Proceduresfortheroutineradiationprocess-ingofbloodproduct(bloodandbloodcomponents)arealsogiven.Iffollowed,theseprocedureswillhelpensurethatbloodproductexposedtogammaradiationorX-radiation(bremsstrahlung)willreceiveabsorbeddoseswithaspecifiedrange.1.2Thispracticecoversdosimetryfortheirradiationofbloodproductforself-containedirradiators(free-standingirradiators)utilizingradionuclidessuchas137Csand60Co,orX-radiation(bremsstrahlung).Theabsorbeddoserangeforbloodirradiationistypically15Gyto50Gy.1.3ThephotonenergyrangeofX-radiationusedforbloodirradiationistypicallyfrom40keVto300keV.1.4Thispracticealsocoverstheuseofradiation-sensitiveindicatorsforthevisualandqualitativeindicationthattheproducthasbeenirradiated(seeISO/ASTMGuide51539).1.5ThisdocumentisoneofasetofstandardsthatprovidesrecommendationsforproperlyimplementingdosimetryinradiationprocessinganddescribesameansofachievingcompliancewiththerequirementsofISO/ASTMPractice52628fordosimetryperformedforbloodirradiation.ItisintendedtobereadinconjunctionwithISO/ASTMPractice52628.1.6Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesandtodeterminetheapplicabilityorregulatorylimitationspriortouse.2.Referenceddocuments2.1ASTMStandards:2E170TerminologyRelatingtoRadiationMeasurementsandDosimetry2.2ISO/ASTMStandards:251026PracticeforUsingtheFrickeDosimetrySystem51261PracticeforCalibrationofRoutineDosimetrySys-temsforRadiationProcessing51275PracticeforUseofaRadiochromicFilmDosimetrySy...
