Designation:D6259−15(Reapproved2019)AnAmericanNationalStandardStandardPracticeforDeterminationofaPooledLimitofQuantitationforaTestMethod1ThisstandardisissuedunderthefixeddesignationD6259;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thispracticecoverstheuseofstandardregressiontechniquesanddatafromaninterlaboratorystudytodeterminealowerquantitativelimitforatestmethod.Thisdeterminedlowerlimitrepresentsthenumericallimitatorabovewhichthetestresultsareconsideredtobequantitativelymeaningfulforcommerceorregulatoryactivitiesbythispractice.Itisdefinedbythisstandardasthepooledlimitofquantitation(PLOQ)forthetestmethod.1.2Thispracticeisapplicabletotestmethodsthatarecapableofproducingnumericaltestresultsclosetozero.Examplesarethosetestmethodsthatdeterminequantitativelytheconcentrationofanalyte(s)nearzero.1.3Thisinternationalstandardwasdevelopedinaccor-dancewithinternationallyrecognizedprinciplesonstandard-izationestablishedintheDecisiononPrinciplesfortheDevelopmentofInternationalStandards,GuidesandRecom-mendationsissuedbytheWorldTradeOrganizationTechnicalBarrierstoTrade(TBT)Committee.2.ReferencedDocuments2.1ASTMStandards:2D6300PracticeforDeterminationofPrecisionandBiasDataforUseinTestMethodsforPetroleumProductsandLubricantsE456TerminologyRelatingtoQualityandStatisticsE691PracticeforConductinganInterlaboratoryStudytoDeterminethePrecisionofaTestMethod3.Terminology3.1Definitions:3.1.1repeatabilityconditions,n—conditionsunderwhichtestresultsareobtainedwiththesametestmethodinthesamelaboratorybythesameoperatorwiththesameequipmentintheshortestpracticalperiodoftimeusingtestunitsortestspecimenstakenatrandomfromasinglequantityofmaterialthatisasnearlyhomogeneousaspossible.NOTE1—Byintheshortestpracticalperiodoftimeismeantthatthetestresults,atleastforonematerial,areobt...
