ASTM_D_5400_-_03_2013.pdf

Designation:D540003(Reapproved 2013)Standard Test Methods forHydroxypropylcellulose1This standard is issued under the fixed designation D5400;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1.Scope1.1 These test methods cover the testing of hydroxypropy-lcellulose.1.2 The test procedures appear in the following order:SectionsMoisture4 9Viscosity10 16pH17 21Residue on Ignition22 28Hydroxypropoxy Content29 361.3 The values stated in SI units are to be regarded as thestandard.The values given in parentheses are for informationonly.1.4 This standard does not purport to address all of thesafety concerns,if any,associated with its use.It is theresponsibility of the user of this standard to establish appro-priate safety and health practices and determine the applica-bility of regulatory limitations prior to use.For specific hazardstatements,see 26.6.2.Referenced Documents2.1 ASTM Standards:2D3876 Test Method for Methoxyl and Hydroxypropyl Sub-stitution in Cellulose Ether Products by Gas Chromatog-raphyE70 Test Method for pH of Aqueous Solutions With theGlass Electrode3.Reagents3.1 Purity of ReagentsReagent grade chemicals shall beused in all tests.Unless otherwise indicated,it is intended thatall reagents shall conform to the specifications of the Commit-tee on Analytical Reagents of the American Chemical Society,where such specifications are available.3Other grades may beused,provided it is first ascertained that the reagent is ofsufficiently high purity to permit its use without lessening theaccuracy of the determination.3.2 Purity of WaterUnless otherwise indicated,referencesto water shall be understood to mean distilled water.MOISTURE4.Scope4.1 This test method covers the determination of the volatilecontent of hydroxypropylcellulose.5.Significance and Use5.1 The results of this test are used for calculating the totalsolids in the sample;and,by common usage,all materialsvolatile at this test temperature are designated as moisture.5.2 Moisture analysis(along with residue on ignition)is ameasure of the amount of active polymer in the material andmust be considered when determining the amount of hydroxy-propylcellulose to use in various formulations.6.Apparatus6.1 Oven,gravity convection,capable of maintaining atemperature of 105 6 3C.6.2 Weighing Dish,glass or aluminum,with cover,50 mmin diameter,25 mm in height,or equivalent.6.3 Analytical Balance.7.Procedure7.1 Weigh about 5 g of sample to the nearest 0.001 g in atared and covered weighing dish.7.2 Place it in an oven at 105 6 1C for 3 h with the coverremoved.7.3 Remove the dish from the oven,immediately replace thecover,cool in a desiccator,and weigh.1These test methods are under the jurisdiction of ASTM Committee D01 onPaint and Related Coatings,Materials,and Applications and are the directresponsibility of Subcommittee D01.36 on Cellulose and Cellulose Derivatives.Current edition approved June 1,2013.Published June 2013.Originallyapproved in 1993.Last previous edition approved in 2008 as D5400 03(2008).DOI:10.1520/D5400-03R13.2For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.3Reagent Chemicals,American Chemical Society Specifications,AmericanChemical Society,Washington,DC.For suggestions on the testing of reagents notlisted by the American Chemical Society,see Analar Standards for LaboratoryChemicals,BDH Ltd.,Poole,Dorset,U.K.,and the United States Pharmacopeiaand National Formulary,U.S.Pharmacopeial Convention,Inc.(USPC),Rockville,MD.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United States1 8.Calculation8.1 Calculate the percent moisture,M,as follows:M 5A/B!3100(1)where:A=mass loss on heating,g,andB=sample used,g.8.2 Report the moisture content to the nearest 0.1%.9.Precision and Bias9.1 PrecisionStatistical analysis of intralaboratory testresults on samples containing from 1 to 6%moisture indicatesa precision of 60.2%absolute at the 95%confidence level.9.2 BiasNo justifiable statement on bias can be made asno suitable reference material is available as a standard.VISCOSITY10.Scope10.1 This test method is an arbitrary method of determiningthe viscosity of aqueous solutions of hydroxypropylcellulose inthe viscosity range of 10 to 16 000 cP/s at 25C.10.2 The concentration to be used for the test shall beagreed upon between the purchaser and the seller.It shall besuch that the viscosity of the solution will fall within the rangeof this test.10.3 The results for the viscosity of hydroxypropylcelluloseby this test method will not necessarily check with results fromother types of instrument