ASTM_D_612_-_88_2012.pdf

Designation:D61288(Reapproved 2012)Standard Test Method forCarbonizable Substances in Paraffin Wax1This standard is issued under the fixed designation D612;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.This standard has been approved for use by agencies of the U.S.Department of Defense.1.Scope1.1 This test method covers determination of carbonizablesubstances in paraffin wax.The test method is applicable toparaffin wax for pharmaceutical use,as defined by the U.S.National Formulary,with a melting point as determined inaccordance with Test Method D87,between 117 and 149F(47and 65C).1.2 The values stated in inch-pound units are to be regardedas standard.The values given in parentheses are mathematicalconversions to SI units that are provided for information onlyand are not considered standard.1.3 This standard does not purport to address all of thesafety concerns,if any,associated with its use.It is theresponsibility of the user of this standard to establish appro-priate safety and health practices and determine the applica-bility of regulatory limitations prior to use.Specific warningstatements are given in Annex A1.2.Referenced Documents2.1 ASTM Standards:2D87 Test Method for Melting Point of Petroleum Wax(Cooling Curve)D1193 Specification for Reagent Water3.Summary of Test Method3.1 Five millilitres of melted wax are treated with 5 mL ofconcentrated,nitrogen-free sulfuric acid at 158F(70C).Thecolor of the acid layer is compared with that of a colorimetricreference standard.If the color is not darker than the standard,the wax is reported as passing the test.4.Significance and Use4.1 This test method is a means for ascertaining whetherpharmaceutical paraffin wax conforms to the standards forquality prescribed by the U.S.National Formulary.5.Apparatus5.1 Test Tube,as shown in Fig.1,of heat-resistant glass3fitted with a well-ground glass stopper,the stopper and the tubebearing identical and indestructible numbers.The tube shall be140 6 2 mm in length and between 14.5 and 15.0 mm inoutside diameter,and shall be calibrated at the 5 6 0.2-mL and10 6 0.2-mL liquid levels.The capacity of the tube withstopper inserted shall be between 13.6 and 15.6 mL.A rollededge may be provided for suspending the tube on the cover ofthe water bath.5.2 Water Bath,suitable for immersing the test tube abovethe 10-mL line and equipped to maintain a temperature of 1586 1.0F(70 6 0.5C).The bath shall be provided with a coverof any suitable material,with holes approximately 16 mm indiameter through which the test tubes may be suspended.5.3 Color Comparator,of a suitable type for observing thecolor of the acid layer in comparison with the referencestandard color solution.The size and shape of the comparatorare optional,but the size and shape of the apertures shallconform to the dimensions prescribed in Fig.1.6.Reagents6.1 Purity of ReagentsReagent grade chemicals shall beused in all tests.Unless otherwise indicated,it is intended thatall reagents shall conform to the specifications of the Commit-tee on Analytical Reagents of the American Chemical Society,where such specifications are available.4Other grades may beused,provided it is first ascertained that the reagent is ofsufficiently high purity to permit its use without lessening theaccuracy of the determination.1This test method is under the jurisdiction of ASTM Committee D02 onPetroleum Products,Liquid Fuels,and Lubricants and is the direct responsibility ofSubcommittee D02.10.0A on Physical/Chemical Properties.Current edition approved Nov.1,2012.Published November 2012.Originallyapproved in 1941.Last previous edition approved in 2007 as D61288(2007).DOI:10.1520/D0612-88R12.2For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.3Borosilicate glass has been found satisfactory for this purpose.4Reagent Chemicals,American Chemical Society Specifications,AmericanChemical Society,Washington,DC.For Suggestions on the testing of reagents notlisted by the American Chemical Society,see Annual Standards for LaboratoryChemicals,BDH Ltd.,Poole,Dorset,U.K.,and the United States Pharmacopeiaand National Formulary,U.S.Pharmacopeial Convention,Inc.(USPC),Rockville,MD.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United States1 6.2 Purity of WaterUnless otherwise indicated,referencesto water shall be understood to mean distilled water,such asreagent water corresponding to Specification D1193,Type III,or water of equal purity.6.3 Cobaltous Chloride Solution(0.5 N)Dissolve about65 g of cobaltous chloride(CoCl26H2O)in enough dilutedhydroc