ASTM_D_6561_-_06_2011.pdf

Designation:D656106(Reapproved 2011)Standard Test Method forDetermination of Aerosol Monomeric and OligomericHexamethylene Diisocyanate(HDl)in Air with(Methoxy-2phenyl-1)Piperazine(MOPIP)in the Workplace1This standard is issued under the fixed designation D6561;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1.Scope1.1 This test method covers the determination of aerosolhexamethylene diisocyanate(HDI)in air samples collectedfrom workplace and ambient atmospheres.The method de-scribed in this test method collects separate fractions.Onefraction will be dominated by vapor,and the other fraction willbe dominated by aerosol.It is not known at the present timewhether this represents a perfect separation of vapor andaerosol,and in any case,there are not separate exposurestandards for vapor and aerosol.Therefore,in comparing theresults for isocyanate against a standard,results from the twofractions should be combined to give a single total value.Thereason for splitting the sample into two fractions is to increaseanalytic sensitivity for the vapor fraction and also to give thehygienist or ventilation engineer some information concerningthe likely state of the isocyanate species.The analyses of thetwo fractions are different,and are provided in separate,linked,standards to avoid confusion.This test method is principallyused to determine short term exposure(15 min)of HDI inworkplace environments for personal monitoring or in ambientair.The analysis of the vapor fraction is performed separately,as described in Test Method D6562.1.2 Differential air sampling is performed with a segregat-ing device.2The aerosol fraction is collected on a polytetra-fluoroethylene(PTFE)filter.1.3 Immediately after sampling,the PTFE filter is trans-ferred into a jar containing a(methoxy-2 phenyl-1)piperazine(MOPIP)solution in toluene.1.4 The analysis of the aerosol fraction is performed byusing a high performance liquid chromatograph(HPLC)equipped with an ultraviolet(UV)detector.The range ofapplication of the test method has been validated from 0.052 to1.04 g of monomeric HDI/mL,which corresponds,based ona 15 Lair sample,to concentrations from 0.004 to 0.070 mg/m3of HDI.Those concentrations correspond to a range of aerosolphase concentrations from 0.5 ppb(V)to 10 ppb(V)and coverthe established threshold limit valve(TLV)value of 5 ppb(V).1.5 The quantification limit for the monomeric HDI is 0.041g per mL,which corresponds to 0.003 mg/m3for a 15 Lsampled air volume.This value is equivalent to ten times thestandard deviation obtained from ten measurements carried outon a standard solution in contact with the PTFE filter whoseconcentration of 0.1 g/mL is close to the expected detectionlimit.1.6 This standard does not purport to address all of thesafety concerns,if any,associated with its use.It is theresponsibility of the user of this standard to establish appro-priate safety and health practices and determine the applica-bility of regulatory limitations prior to use.See Section 9 foradditional hazards.2.Referenced Documents2.1 ASTM Standards:3D1193 Specification for Reagent WaterD1356 Terminology Relating to Sampling and Analysis ofAtmospheresD1357 Practice for Planning the Sampling of the AmbientAtmosphereD5337 Practice for Flow Rate Adjustment of Personal Sam-pling PumpsD6562 Test Method for Determination of Gaseous Hexam-ethyleneDiisocyanate(HDI)inAirwith9-(N-methylaminomethyl)Anthracene Method(MAMA)in theWorkplace1This test method is under the jurisdiction of ASTM Committee D22 on AirQuality and is the direct responsibility of Subcommittee D22.04 on Workplace AirQuality.Current edition approved Oct.1,2011.Published October 2011.Originallyapproved in 2000.Last previous edition approved in 2006 as D6561-06.DOI:10.1520/D6561-06R11.2The sampling device for isocyanates is covered by a patent held by JacquesLesage et al,IRSST,505 De Maisonneuve Blvd.West,Montreal,Quebec,Canada.If you are aware of an alternative to this patented item,please provide thisinformation to ASTM Headquarters.Your comments will receive careful consider-ation at a meeting of the responsible technical committee,1which you may attend.3For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United States1 2.2 Other Standard:4Sampling Guide for Air Contaminants in the Workplace3.Terminology3.1 For definitions of terms used in this test method,refer toTerminology D13564.Summary of Test Method4.1 Vapor and aerosol fractions are sampled simultaneouslyby using a segregatin