ASTM_D_7510_-_10_2016e1.pdf

Designation:D751010(Reapproved 2016)1Standard Practice forPerforming Detection and Quantitation Estimation and DataAssessment Utilizing DQCALC Software,based on ASTMPractices D6091 and D6512 of Committee D19 on Water1,2This standard is issued under the fixed designation D7510;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1NOTEReapproved with editorial change to 4.2.3 in December 2016.1.Scope1.1 This software was developed to automate calculationswithin three ASTM standards:Practices D2777(outlier re-moval section),D6091,and D6512.1.2 The program calculates detection estimates(DE)andquantitation estimates(QE)for the constant,straight-line,exponential,and hybrid(Rocke-Lorenzato)models of thevariation of inter or intra laboratory standard deviation(ILSD)with concentration.Calculations are shown in theDE_QE worksheet and results are shown in the DLs&QLsworksheet.Several plots are generated showing how well eachmodel fits the data.The least complex model to fit the data withadequate confidence must be used by the ASTM standards.NOTE1Modeling techniques automated in this practice and with thissoftware have been shown to work well with most data sets.Users of thissoftware are cautioned that with some,rare data sets,anomalous resultsmay be obtained,and manual forcing of a different model may berequired.It has been noted that for some data sets when an exponentialmodel is selected,there may be a lack of convergence on a result or theremay be a convergence on two separate results.1.3 Users of DQCALC should refer to Practices D2777,D6091,and D6512 for the specifics of the scope and applica-tion of the Practices.1.4 The IDE Practice(D6091)and the IQE Practice(D6512)are concerned with estimates of limits of detectionand limits of quantitation based on inter-laboratory data.DQCALC may also be employed to calculate detection andquantitation estimates based on single laboratory data.1.5 The DQCALC Software consists of a Microsoft Excel3workbook spreadsheet and associated macros and a usermanual in Microsoft Word.32.Referenced Documents2.1 ASTM Standards:4D2777 Practice for Determination of Precision and Bias ofApplicable Test Methods of Committee D19 on WaterD6091 Practice for 99%/95%Interlaboratory DetectionEstimate(IDE)for Analytical Methods with NegligibleCalibration ErrorD6512 Practice for Interlaboratory Quantitation Estimate2.2 ASTM Adjuncts:DQCALC Microsoft Excel-based software for the Inter-laboratory Quantitation Estimate(IQE)23.Terminology3.1 Definitions of Terms Specific to This Standard:3.1.1 batchthe samples associated with a given samplepreparation.If all laboratories analyze samples prepared atthree different times then results from each sample preparationwould be considered a distinct batch.3.1.2 p-valueprobability value associated with curvature,the smaller the value the higher the likelihood of curvature(0.05 is acceptable).3.1.3 Q-valueQ must be positive and the associated prob-ability of Q(pQ-value)which is related to curvature must be0.05.3.2 Acronyms:3.2.1 DEdetection estimate3.2.2 IDEinterlaboratory detection estimate3.2.3 ILSDinter or intra/within laboratory standard de-viation3.2.4 IQEinterlaboratory quantitation estimate3.2.5 QEquantitation estimate3.2.6 SSRsum-of-squared residuals1This practice is under the jurisdiction of ASTM Committee D19 on Water andis the direct responsibility of Subcommittee D19.02 on Quality Systems,Specification,and Statistics.Current edition approved Dec.15,2016.Published December 2016.Originallyapproved in 2010.Last previous edition approved in 2010 as D7510 10.DOI:10.1520/D7510-10R16E01.2DQCALC is available from ASTM International Headquarters.Order AdjunctNo.ADJDQCALC.Original adjunct produced in 2007.3Trademark of Microsoft,Redmond,WA,98052.4For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United States1 3.2.7 WDEwithin-lab detection estimate3.2.8 WQEwithin-lab quantitation estimate4.Minimum Requirements4.1 DQCALC is based on an Microsoft Excel3spreadsheetworkbook.4.2 DQCALC requires the following minimum hardwareand operating system configuration to function properly:4.2.1 IBM-compatible PC with a Pentium microprocessor(or equivalent),133 Mhz or faster.4.2.2 Windows 2000 or XP.4.2.3 Excel 2000,2002(XP),2003,2010,or 2013.Currently,DQCALC does not work with Microsoft Excel32008 or 2016.4.2.4 32 MB RAM,plus minimum of 23 MB free diskspace for each file to be processed.4.2.5 Color video monitor,using a standard 1024 768screen resolution.The program will