Designation:D6561−20StandardTestMethodforDeterminationofAerosolMonomericandOligomericHexamethyleneDiisocyanate(HDl)inAirwith(Methoxy-2–phenyl-1)Piperazine(MOPIP)intheWorkplace1ThisstandardisissuedunderthefixeddesignationD6561;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thistestmethodcoversthedeterminationofaerosolhexamethylenediisocyanate(HDI)inairsamplescollectedfromworkplaceandambientatmospheres.Themethodde-scribedinthistestmethodcollectsseparatefractions.Onefractionwillbedominatedbyvapor,andtheotherfractionwillbedominatedbyaerosol.TheresultsobtainedfromtheanalysisoftheseparatefractionsdonotnecessarilyrepresentthetruepartitionofthemeasuredHDIphysicalphases,andshouldonlybeconsideredarepresentationofthegeneraltrendinthephysicalphasepartitionwithinsamples.Theanalysesofthetwofractionsaredifferent,andareprovidedinseparate,linked,standardstoavoidconfusion.Thistestmethodisprincipallyusedtodetermineshorttermexposure(15min)ofHDIinworkplaceenvironmentsforpersonalmonitoringorinambientair.Theanalysisofthevaporfractionisperformedseparately,asdescribedinTestMethodD6562.1.2Differentialairsamplingisperformedwithasegregat-ingdevice.Theaerosolfractioniscollectedonapolytetrafluo-roethylene(PTFE)filter.1.3Theanalysisoftheaerosolfractionisperformedbyusingahighperformanceliquidchromatograph(HPLC)equippedwithanultraviolet(UV)detector.Anultrahighperformanceliquidchromatograph(UPLC)canalsobeused,providedthatitsperformanceisequivalenttowhatisstatedinthisstandard.Therangeofapplicationofthetestmethodhasbeenvalidatedfrom0.052to1.04µgofmonomericHDI/mL,whichcorresponds,basedona15Lairsample,toconcentra-tionsfrom0.004to0.070mg/m3ofHDI.Thoseconcentrationscorrespondtoarangeofaerosolphaseconcentrationsfrom0.5ppb(V)to10ppb(V)andcovertheestablishedthresholdlimitvalve(TLV)value...
