Designation:D7600−16(Reapproved2017)StandardTestMethodforDeterminationofAldicarb,Carbofuran,OxamylandMethomylbyLiquidChromatography/TandemMassSpectrometry1ThisstandardisissuedunderthefixeddesignationD7600;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thisprocedurecoversthedeterminationofaldicarb,carbofuran,oxamylandmethomyl(referredtocollectivelyascarbamatesinthistestmethod)insurfacewaterbydirectinjectionusingliquidchromatography(LC)anddetectedwithtandemmassspectrometry(MS/MS).Theseanalytesarequali-tativelyandquantitativelydeterminedbythistestmethod.Thistestmethodadherestomultiplereactionmonitoring(MRM)massspectrometry.1.2ThistestmethodhasbeendevelopedbyU.S.EPARegion5ChicagoRegionalLaboratory(CRL).1.3ThevaluesstatedinSIunitsaretoberegardedasstandard.Nootherunitsofmeasurementareincludedinthisstandard.1.4TheDetectionVerificationLevel(DVL)andReportingRangeforthecarbamatesarelistedinTable1.1.4.1TheDVLisrequiredtobeataconcentrationatleast3timesbelowtheReportingLimit(RL)andhaveasignal/noiseratiogreaterthan3:1.Fig.1displaysthesignal/noiseratiosoftheprimarysinglereactionmonitoring(SRM)transi-tionsandFig.2displaystheconfirmatorySRMtransitionsattheDVLsforthecarbamates.1.4.2ThereportinglimitistheconcentrationoftheLevel1calibrationstandardasshowninTable2forthecarbamates.1.5Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.1.6Thisinternationalstandardwasdevelopedinaccor-dancewithinternationallyrecognizedprinciplesonstandard-izationestablishedintheDecisiononPrinciplesfortheDevelopmentofInternationalStandards,GuidesandRecom-mendationsissuedbytheWorldTradeOrganizationTechnica...
