ASTM_D_7979_-_17.pdf

Designation:D797917Standard Test Method forDetermination of Per-and Polyfluoroalkyl Substances inWater,Sludge,Influent,Effluent and Wastewater by LiquidChromatography Tandem Mass Spectrometry(LC/MS/MS)1This standard is issued under the fixed designation D7979;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1.Scope1.1 This procedure covers the determination of selected per-and polyfluoroalkyl substances(PFASs)in a water matrixusing liquid chromatography(LC)and detection with tandemmass spectrometry(MS/MS).These analytes are qualitativelyand quantitatively determined by this method.This methodadheres to a technique known as selected reaction monitoring(SRM)or sometimes referred to as multiple reaction monitor-ing(MRM).This is not a drinking water method,performanceof this test method has not been evaluated on drinking watermatrices.1.2 The Method Detection Limit(MDL)2and ReportingRange3for the target analytes are listed in Table 1.The targetconcentration for the reporting limit for this test method was 10ng/L for most of the target analytes at the time of development.1.2.1 The reporting limit in this test method is the minimumvalue below which data are documented as non-detects.Thereporting limit may be lowered providing your lab meets theminimum performance requirements of this test method at thelower concentrations,this method is performance based andmodifications are allowed to improve performance.Analytedetections between the method detection limit and the report-ing limit are estimated concentrations and are not reportedfollowing this test method.In most cases,the reporting limit isthe concentration of the Level 1 calibration standard as shownin Table 4 for the PFASs after taking into account the 50%dilution with methanol.It is above the Level 1 calibrationconcentration for FHEA and FOEA,these compounds can beidentified at the Level 1 concentration but the standard devia-tion among replicates at this lower spike level resulted in ahigher reporting limit.1.3 The values stated in SI units are to be regarded asstandard.No other units of measurement are included in thisstandard.1.4 This standard does not purport to address all of thesafety concerns,if any,associated with its use.It is theresponsibility of the user of this standard to establish appro-priate safety,health and environmental practices and deter-mine the applicability of regulatory limitations prior to use.1.5 This international standard was developed in accor-dance with internationally recognized principles on standard-ization established in the Decision on Principles for theDevelopment of International Standards,Guides and Recom-mendations issued by the World Trade Organization TechnicalBarriers to Trade(TBT)Committee.2.Referenced Documents2.1 ASTM Standards:4D1129 Terminology Relating to WaterD1193 Specification for Reagent WaterD2777 Practice for Determination of Precision and Bias ofApplicable Test Methods of Committee D19 on WaterD3856 Guide for Management Systems in LaboratoriesEngaged in Analysis of WaterD3694 Practices for Preparation of Sample Containers andfor Preservation of Organic ConstituentsD4841 Practice for Estimation of Holding Time for WaterSamples Containing Organic and Inorganic ConstituentsD5847 Practice for Writing Quality Control Specificationsfor Standard Test Methods for Water AnalysisE2554 Practice for Estimating and Monitoring the Uncer-tainty of Test Results of a Test Method Using ControlChart Techniques1This test method is under the jurisdiction of ASTM Committee D19 on Waterand is the direct responsibility of Subcommittee D19.06 on Methods forAnalysis forOrganic Substances in Water.Current edition approved July 15,2017.Published August 2017.Originallyapproved in 2015.Last previous edition approved in 2016 as D7979 16.DOI:10.1520/D7979-17.2The MDL is determined following the Code of Federal Regulations(CFR),40CFR Part 136,Appendix B utilizing dilution and filtration.5 mL sample of waterwas utilized.A detailed process determining the MDL is explained in the referenceand is beyond the scope of this test method to be explained here.3Reporting range concentration is calculated from Table 4 concentrationsassuming a 30 L injection of the Level 1 calibration standard for PFASs,and thehighest level calibration standard with a 10 mL final extract volume of a 5 mL watersample.Volume variations will change the reporting limit and ranges.4For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United StatesThis internati