Designation:E1601−12StandardPracticeforConductinganInterlaboratoryStudytoEvaluatethePerformanceofanAnalyticalMethod1ThisstandardisissuedunderthefixeddesignationE1601;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thispracticecoversproceduresandstatisticsforaninterlaboratorystudy(ILS)oftheperformanceofananalyticalmethod.Thestudyprovidesstatisticalvalueswhichareusefulindeterminingifamethodissatisfactoryforthepurposesforwhichitwasdeveloped.Thesestatisticalvaluesmaybeincorporatedinthemethod’sprecisionandbiassection.Thispracticediscussesthemeaningofthestatisticsandwhatusersofanalyticalmethodsmaylearnfromthem.1.2Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.2.ReferencedDocuments2.1ASTMStandards:2E135TerminologyRelatingtoAnalyticalChemistryforMetals,Ores,andRelatedMaterialsE177PracticeforUseoftheTermsPrecisionandBiasinASTMTestMethodsE691PracticeforConductinganInterlaboratoryStudytoDeterminethePrecisionofaTestMethodE1169PracticeforConductingRuggednessTestsE1763GuideforInterpretationandUseofResultsfromInterlaboratoryTestingofChemicalAnalysisMethods3.Terminology3.1Definitions—Fordefinitionsoftermsusedinthispractice,refertoTerminologyE135.3.2DefinitionsofTermsSpecifictoThisStandard:3.2.1interlaboratorytest—measuresthevariabilityofre-sultswhenatestmethodisappliedmanytimesinanumberoflaboratories.3.2.2replicateresults—resultsobtainedbyapplyingatestmethodaspecifiednumberoftimestoamaterial.3.2.3testprotocol—givesinstructionstoeachparticipatinglaboratory,detailingthewayitistoconductitspartoftheinterlaboratorytestprogram.4.SummaryofPractice4.1Instructionsareprovidedforp...
