Designation:E1302−13AnAmericanNationalStandardStandardGuideforAcuteAnimalToxicityTestingofWater-MiscibleMetalworkingFluids1ThisstandardisissuedunderthefixeddesignationE1302;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope*1.1Thisguidedefinesacuteanimaltoxicitytestsandsetsforththereferencesforprocedurestoassesstheacutetoxicityofwater-misciblemetalworkingfluidsasmanufactured.1.2Althoughwater-misciblemetalworkingfluidsaretypi-callyusedathighdilution,dilutionratesvarywidely.Additionally,thereispotentialforexposuretothemetalwork-ingfluidasmanufactured.1.3Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.2.ReferencedDocuments2.1ASTMStandards:2E758TestMethodforMammalianAcutePercutaneousTox-icity(Withdrawn2010)3E981TestMethodforEstimatingSensoryIrritancyofAir-borneChemicalsE993TestMethodforEvaluationofDelayedContactHy-persensitivity(Withdrawn2010)3E1103TestMethodforDeterminingSubchronicDermalToxicity(Withdrawn2010)3E1542TerminologyRelatingtoOccupationalHealthandSafetyE2523TerminologyforMetalworkingFluidsandOpera-tions2.2CPSCStandards:416CFRPart150016CFRPart1500.316CFRPart1500.4016CFRPart1500.4116CFRPart1500.422.3DOTStandards:449CFRPart173,AppendixA49CFRPart173.343a149CFRPart173.343a249CFRPart173.343a32.4EPA–TSCAStandards:440CFR79240CFR870.110040CFR870.120040CFR870.130040CFR870.240040CFR870.250040CFR870.26002.5OSHAStandards:429CFR1910.120029CFR1910.1200AppendixA,3(a)and6(a)29CFR1910.1200AppendixA,3(b)and6(b)29CFR1910.1200AppendixA,3(c)and6(c)29CFR1910.1200AppendixA,43.Terminology3.1Fordefinitionsoftermsinthispracticerelatingtotoxicologicaltesting,refertoTerminologyE2523.Fo...
