第二章杀虫剂(insecticide)本章的重点和难点1.有机磷中间体的制备；2.磷酸酯、一硫（酮）代磷酸酯、二硫（酮、酮）代磷酸酯、磷酰胺酯以及膦酸酯的合成；3.亚磷酸二烷基酯、亚磷酸三烷基酯与-卤代碳基化合物的反应；4.氨基甲酸酯类杀虫剂的合成；5.几种常见菊酸、醇中间体及除虫菊酯的合成。第一节有机氯杀虫剂ClHCCl3CClDDTClClClClClCl±ûÌåÁùÁùÁùCH3OCHCCl3OCH3¼×ÑõµÎµÎÌéClClCClOSOClClOÁòµ¤CHCCl3OCOCH3ClClÈýÂÈɱòýõ¥第一节有机氯杀虫剂一、有机磷杀虫剂的结构与分类1.有机磷杀虫剂的化学结构R1¡¢R2ΪÍé»ù¡¢ÍéÑõ»ù¡¢ÍéÁò»ù¡¢°·»ùµÈO»òSÖ±½ÓÁ¬½ÓÔÚÎå¼ÛÁ×ÉÏ¡°õ£»ù¡±Îª´ú±íÓлú»òÎÞ»úËáµÄÒõÀë×ÓÈçF-¡¢CN-¡¢ë¿¸ºÀë×Ó¡¢Áò´¼¸ºÀë×ÓµÈPR1R2O£¨S£©õ£»ù第二节有机磷杀虫剂(OrganophosphorousPesticides)•2.有机磷杀虫剂的分类（1）磷酸酯类（phosphate）：POOOO(CH3O)2POOCHCClClµÐµÐη(CH3O)2POOCCHCONHCH3CH3¾ÃЧÁ×第二节有机磷杀虫剂(OrganophosphorousPesticides)POOSOPOOOSPOOSSPOSOSSCH3CH3±¶ÁòÁ×(CH3O)2PSO(CH3O)2PSSCH2CNHCH3OÀÖ¹û（2）硫代磷酸酯（sulphosphate）：第二节有机磷杀虫剂(OrganophosphorousPesticides)PCH3OCH3SONHRR=H£¬¼×°·Á×R=CONHCH3£¬ÒÒõ£¼×°·Á×（3）磷酰胺酯（phosphoroamidate)：（4）焦磷酸酯（pyrophosphate)：(C2H5O)2PSOP(OC2H5)2SÖÎÃøÁ×(CH3)2N2POOPN(CH3)22O°Ë¼×Á×第二节有机磷杀虫剂(OrganophosphorousPesticides)(CH3O)2POCHCCl3OHµÐ°Ù³æPC6H5C2H5OSONO2±½ÁòÁ×（5）膦酸酯（phosphomate)：第二节有机磷杀虫剂(OrganophosphorousPesticides)二、有机磷杀虫剂研究开发动向1．不对称（asymmetry）有机磷杀虫剂PSCH3OH2NOSCH3CH3±½°·ÁòÁ×PCH3O(CH3)2CHNHSOCOOCH(CH3)2¼×»ùÒìÁøÁ×PC2H5OC3H7SSOnClCl±ûÁòÁ×BrClnPC2H5OC3H7SOO±ûäåÁ×第二节有机磷杀虫剂(OrganophosphorousPesticides)NNOPC2H5OC2H5OSOßÕàºÁòÁ×PC2H5OC2H5OSONNOCH3CH3à×à¤ÑõÁ×2．引入杂环CH3CH(CH3)2NNPC2H5OC2H5OSO¶þàºÁ×¼×»ùßòÁ×(CH3O)2PSONO第二节有机磷杀虫剂(OrganophosphorousPesticides)PC2H5OC2H5OSONNClßÁßòÁòÁ×PC2H5...
