新生儿导管相关性感染Welcometothehospital!Bugsarewaitingforyou!!WhyWorryaboutNeonatalHospital-acquiredinfections(HAIs)?USA:>2,000,000HAIs/y50-60%由耐药菌引起出生2周后,45%新生儿死亡由晚发性败血症所致HAIs延长住院时间,增加医疗费用,并可影响新生儿神经发育新生儿败血症分类:早发败血症(<72h发病):多与宫内感染有关晚发败血症(>3d发病):多与住院治疗有关Early-Onset2%Late-Onset20%Birth3d30d60d90dVeryLate-Onset1%Timingofinfectioninneonates国内报道胎龄<37周的新生儿,感染率为9.03%,高于胎龄大于37周的新生儿医院感染(4.79%),胎龄越小、体重越低,感染率越高NICU早产儿医院感染发生率可高达25.9%,病死率可高达30%Birthweight(g)CRBSI*VAP*<100010.3%2.0%1001-...